A calm look at the evidence
Evidence on brain fog, focus, and cognitive energy.
Brain fog, focus, and cognitive energy are noisy topics. Clearhead Lab reads the primary research slowly, so you can settle on what actually holds up — every claim sourced, and a clear conscience about how we're funded.
Shopping for a nootropic right now? We ranked the big branded stacks by whether the finished product was ever put in a human trial — only 2 of 5 ever were.
Our clearest pick · From $93/mo
CoreAge Rx
NAD+ nasal spray or injection advertised from $93/month, with online clinical review.
Evidence: No rigorous cognition trial. Nasal and injected NAD+ are marketed for cellular energy and focus with no rigorous human cognition or energy trial.
Advertising disclosure · we may earn a commission if you start through this link, at no extra cost to you. See our disclosure.
Things worth reading
What the evidence gently suggests
Unhurried, fully-sourced reviews — written to leave you calmer and clearer, not more anxious about the next thing to buy.
- Evidence note
CoreAge Rx NAD+ Review: $93 Starting Price, Refund Fine Print
CoreAge Rx offers nasal and injectable NAD+ from $93/month. We check the price wording, refund exclusions, care model, and brain-fog evidence.
Read calmly - Evidence note
HealthRX NAD+ Review: $161 Injection Plan and What Is Included
HealthRX publishes NAD+ prices, injection quantity, and prepay terms. Our review checks the $161 plan, nasal option, refunds, and evidence limits.
Read calmly - Evidence note
RxSpan MD NAD+ Review: Routes, Prices, and Visit Fees
RxSpan MD lists NAD+ injection, nasal spray, and flex-dose tablets. We compare $249/$199 base prices, prepay totals, and the consultation-fee caveat.
Read calmly - Evidence note
Willow NAD+ Review: $199 Plan, Supply, and Support
Willow advertises NAD+ injections at $199/month. We review the schedule, support, pharmacy disclosures, subscription caveats, and cognitive evidence.
Read calmly - Evidence note
Enhance MD NAD+ Review: Read the Four-Week Billing First
Enhance MD offers NAD+ injections and wafers. We compare four-week billing, longer plans, support, pharmacy disclosures and the limits of the evidence.
Read calmly - Evidence note
AgelessRx NAD+ Review: Intro Pricing, Three Formats and Evidence
AgelessRx NAD+ reviewed: the $79 injection introduction, $149 follow-on rate, nasal and patch options, cancellation and what its research actually shows.
Read calmly - Evidence note
Hone Health NAD+ Review: $199 Standalone or Membership Pricing
Hone offers NAD+ without a membership for $199/month. We compare the $165 member rate, Basic fees, physician review and questions to settle before buying.
Read calmly - Evidence note
Long-COVID Brain Fog: Symptoms, Evaluation, and Daily Life
A practical guide to cognitive symptoms after COVID, clinical evaluation, post-exertional malaise, and planning work around your current limits.
Read calmly
Provider reviews
NAD+ providers, reviewed one at a time
What each one charges, what the price includes, and what we found on their own site — in the same order as our ranking.
- CoreAge Rx reviewNAD+ nasal spray or injection advertised from $93/month, with online clinical review.From $93/mo
- HealthRX reviewPublishes its whole price ladder in the open — both routes, with the provider visit, the supplies and the shipping already inside the figure.From $134/mo
- RxSpan MD reviewPhysician-led telehealth with three NAD+ routes and its whole price ladder readable before the intake.From $199/mo
- Willow reviewA public $199/month NAD+ injection offer; confirm the prescribed supply and renewal terms.$199/mo
- Enhance MD reviewInjection and sublingual wafer plans with four-week billing and longer prepaid options.From $99/4wks
- Shed reviewThree NAD+ routes at prices that really are the recurring rate — over a two-month minimum term that is printed only in the terms.From $144/mo
- Lttl reviewPublished monthly and prepaid NAD+ plans, with a lower first-month offer and a clear commitment behind the annual headline.$149/mo
- Strut Health reviewOne of the few programs here that prints a milligram beside its price — on a page whose own explanation of what NAD+ is describes a different molecule.From $149
- MyDrHank reviewA public NAD+ starting price qualified by the final prescribed protocol and dose.From $137/mo (protocol dependent)
- Oak reviewNAD+ injection at a published starting price, with provider review, messaging and shipping included.From $175/mo
- Pallas Health reviewNAD+ injection with a first-month promotion and a recurring four-week rate; provider care included.$179/4 wks
- Breeze Meds reviewNames its prescribers and its four compounding pharmacies — then advertises the same NAD+ at three different prices and publishes no terms of service at all.Varies — site conflicts
- Synergy Rx reviewPublishes the whole NAD+ ladder in the open — beside terms saying the final charge may differ from it, and an /about page promising a refund the terms refuse.From $275
- Ageless reviewNames seven dispensing pharmacies and sells NAD+ in two routes — with a listed price its own checkout may change, and a live FDA warning letter filed under a name the brand never uses.From $149/supply
- AgelessRx reviewNAD+ injection, nasal spray and iontophoresis patches with different offer terms.From $125/mo
- Hone Health reviewA standalone NAD+ injection option alongside optional longevity memberships.$199/mo standalone
- He & She MD reviewA published four-term NAD+ price menu; the lowest monthly equivalent requires an annual plan.$229/mo
Evidence, unhurried
Every conclusion traces back to primary research or official labeling — read at a calm pace.
Every claim sourced
Gentle inline citations to the studies, including the null results and the caveats.
Honest about funding
We say so plainly where the evidence behind a product is thin, including for products we earn on.
Read how we work in our editorial policy, and how we stay independent on our about page.