Provider ranking · Updated 2026

Best NAD+ Providers for Energy & Focus (2026), Ranked

NAD+ is sold by telehealth clinics and supplement brands as a way to support cellular energy and focus. We compared the providers that actually offer it on the things that matter once the marketing fades: a transparent price, genuine clinician review, and real human support. CoreAge Rx earns our top spot for value — a flat $93/month NAD+ nasal spray (“Hello Energy”) or injection, doctor-reviewed, 503A-compounded, with included nurse and registered-dietitian consults.

Start with CoreAge Rx — $93/mo How we rank

A calm word before you spend. This is a ranking of provider quality and value, not a claim that NAD+ sharpens your mind. NAD+'s cognitive benefit is unproven, and nasal or IV NAD+ specifically has no rigorous cognition or energy trial. Brain fog is multifactorial — sleep is the single biggest lever, not a supplement. See our full NAD+ for brain fog & focus evidence review first.

A note on how we're funded. We want to be gentle and honest about this: a few links here are affiliate or referral links, and if you choose to start a treatment or buy a product through one, we may earn a commission — at no extra cost to you. It never sways what we recommend. Our picks follow the published evidence and our own careful judgment, full stop. You can read the whole story here.

FTC disclosure. Clearhead Lab has affiliate or referral partnerships with some — not all — of the providers ranked on this page, and we may earn a commission at no extra cost to you when you use our links. Like any comparison site, that compensation can shape which provider we feature and how prominently it appears. The providers we have no commercial tie to still earn their place on the merits, and we link out to them too — they simply don't get the same promotional emphasis. The order itself is set by editorial judgment — price transparency, clinician oversight, and support — and a partnership never buys a higher rank. See our full disclosure.

Our #1 pick · $93 / month, flat

CoreAge Rx

Doctor-reviewed NAD+ nasal spray (“Hello Energy”) with flat pricing and built-in human support.

Featured partner · #1

$93 / month, flat

Form: Nasal spray + injection

U.S.-licensed clinicians review an online intake; the NAD+ protocol is filled by a 503A compounding pharmacy. CoreAge markets the nasal spray (“Hello Energy”) and the injection both at a flat $93/month for cellular energy, focus, and bioavailability. Every plan includes 1:1 consults with a nurse and a registered dietitian, plus an automatic refund if you are not approved for treatment.

Strengths

Transparent flat $93/month — same price for the nasal spray or the injection, no separate membership or lab fee
Doctor-reviewed protocols filled by a 503A compounding pharmacy
Included 1:1 support from a nurse and a registered dietitian
Automatic refund if you are not approved for treatment

Trade-offs

Single-category focus — not a full hormone-optimization clinic
Like all compounded NAD+, it is not an FDA-approved product, and nasal NAD+ has no rigorous cognition trial (see our evidence review)

Start with CoreAge Rx — $93/moAutomatic refund if you are not approved · included nurse + dietitian consults

The rest of the field

Seven more real NAD+ sources, each checked against their own site in 2026 — telehealth clinics offering injections, nasal sprays, and patches, plus the best-evidenced oral NR supplements. We only state a price where the provider published one we could confirm.

AgelessRx

The most established longevity-telehealth clinic — NAD+ as an injection, nasal spray, or iontophoresis patch.

Injection from $185–235/mo; nasal from $125; patch from $160

Form: Injection, nasal spray, transdermal patch

A U.S. longevity-telehealth clinic with a real questionnaire → video → prescriber-review flow and a broad Rx menu (NAD+, plus metformin, LDN, and rapamycin). NAD+ is offered as a self-administered injection, an intranasal spray, or a battery-powered iontophoresis patch, marketed for energy and healthy aging. Cash-pay only, no insurance.

Strengths

Among the most credible longevity-telehealth operators — genuine licensed-prescriber review, not a rubber stamp
Widest NAD+ menu here (injection, nasal, and active iontophoresis patch) so you can match the format to your preference
Injection plans start around $185/mo — closer to CoreAge than the IV-clinic crowd

Trade-offs

Cash-only with a 'longevity Rx' framing; no nurse or registered-dietitian consults bundled like CoreAge
Its nasal and patch absorption claims are unproven — no peer-reviewed human trial shows intranasal or transdermal NAD+ raises cellular NAD+
Per-format pricing means your all-in cost depends on which delivery you pick

Visit AgelessRx Shown for honest comparison — verified on the provider's own site in 2026.

HydraMed

Telehealth NAD+ in three forms with a licensed-provider consult, priced higher than CoreAge.

Injection $299 / month (subscription); $369 one-time

Form: Injection, nasal spray, topical

Online intake plus a telehealth consultation with a licensed provider, then a compounded NAD+ prescription shipped to your door with free shipping and ongoing virtual support. HydraMed markets NAD+ for energy, focus, and reduced brain fog, and offers an injection, a nasal spray, and a 20% topical cream.

Strengths

Three NAD+ formats (injection, nasal spray, topical) under one telehealth program
Licensed-provider telehealth consult, free shipping, and unlimited virtual support

Trade-offs

Injection subscription ($299/month) is over 3× CoreAge's flat $93
No nurse/registered-dietitian consults bundled the way CoreAge includes them
Per-format pricing means the all-in cost depends on what you choose

Visit HydraMed Shown for honest comparison — verified on the provider's own site in 2026.

Hone Health

Well-funded men's-health telehealth clinic that offers a self-administered NAD+ injection alongside its hormone focus.

Injection $165/mo + $25/mo membership (~$190)

Form: Injection

A well-funded ($33M Series A, Jan 2025) telehealth clinic centered on men's hormone optimization, with good doctor reviews and a legitimate prescriber flow. NAD+ is offered as a self-administered injection — an add-on to its core TRT-style catalog rather than the hero product.

Strengths

Real, well-capitalized clinic with solid prescriber reviews
Self-administered injection bypasses the gut, the more plausible NAD+ route

Trade-offs

Stacked fees — the medication, a consult, and a $25/mo membership add up to roughly $190 vs CoreAge's flat $93
TRT-centric: NAD+ is an add-on, not a dedicated program, and no nurse/dietitian support is bundled
Membership-plus-medicine billing draws complaints about the true ongoing cost

Visit Hone Health Shown for honest comparison — verified on the provider's own site in 2026.

Invigor Medical

Established online clinic offering injectable and oral NAD+ with the consult bundled in.

Starting at $340 / month (includes doctor consult and supplies)

Form: Injection + oral

A 100%-online clinic (“prescribed by U.S. doctors”) that ships NAD+ injection or oral NAD+ to your door with the doctor consult and supplies bundled into the price. Invigor markets NAD+ to boost energy and support cognition. A starter fee and first-month promotions can apply.

Strengths

Consult and supplies bundled into the advertised price
Long-running telehealth catalog with both injectable and oral NAD+ options

Trade-offs

Starting price ($340/month) is the highest in this comparison and well above CoreAge's flat $93
Starter fee and shifting first-month promotions make the true ongoing cost harder to pin down
No included nurse or registered-dietitian support

Visit Invigor Medical Shown for honest comparison — verified on the provider's own site in 2026.

Tru Niagen

The benchmark oral NR supplement — patented Niagen, third-party verified, with the strongest human NAD+ data in the category.

$49 / 30ct (~$39 on subscription)

Form: Oral (300mg Niagen NR capsule; also stick packs)

A supplement, not a telehealth program. Tru Niagen (ChromaDex) delivers 300mg of patented Niagen nicotinamide riboside (NR) daily, the most clinically studied NAD+ precursor. It is Alkemist Assured third-party verified, with higher-dose and stick-pack formats NSF Certified for Sport. You buy it directly — no intake, no clinician, no prescription.

Strengths

Strongest evidence in the category — multiple human RCTs show NR meaningfully raises blood NAD+
Genuinely third-party verified (Alkemist Assured; NSF Certified for Sport on some formats) — ChromaDex's own 2025 study found 87% of competitor NR products failed label claims while Niagen passed
Lowest entry price here and no consult to schedule — just buy the bottle

Trade-offs

An over-the-counter supplement with no clinician review, candidate screening, or prescribed protocol
Raising blood NAD+ is not the same as improving cognition or energy — no rigorous trial shows NR sharpens focus
Premium per-dose price and aggressive 'clinically proven' marketing; no nurse or dietitian support

Visit Tru Niagen Shown for honest comparison — verified on the provider's own site in 2026.

Thorne (NiaCel 400)

A trusted practitioner-grade NR supplement from a widely third-party-certified brand.

Pricing varies (~mid-range across retailers)

Form: Oral (NiaCel 400 — ~415mg NR malate capsule)

Thorne is a practitioner-favored supplement brand known for broad third-party certification. NiaCel 400 supplies roughly 415mg of nicotinamide riboside (as NR malate) per serving and is NSF Certified for Sport. Like all supplements here, you buy directly — there is no intake, clinician review, or prescription.

Strengths

Trusted, widely third-party-certified brand; NiaCel 400 is NSF Certified for Sport
Uses NR, the best-evidenced precursor for raising NAD+, at a generous per-serving dose

Trade-offs

Over-the-counter supplement — no clinician oversight or candidate screening
Pricing is opaque and varies across retailers; the NR-malate form differs from the patented Niagen used in trials
Higher blood NAD+ does not equal proven cognitive or energy benefit; no nurse/dietitian support

Visit Thorne (NiaCel 400) Shown for honest comparison — verified on the provider's own site in 2026.

Renue By Science

Direct-to-consumer liposomal NAD+ and NMN supplements — no prescription, no clinician.

NAD+ Complete (liposomal) $84.95; NMN from ~$40

Form: Oral (liposomal capsules, sublingual)

A supplement retailer, not a telehealth provider. Renue sells liposomal NAD+ and NMN capsules and sublingual tabs marketed for cellular energy and healthy aging, with an emphasis on liposomal bioavailability. You buy directly — there is no intake, no clinician review, and no prescription.

Strengths

Lowest entry price and no consult to schedule — just buy the bottle
Oral option for people who do not want an injection or nasal spray

Trade-offs

No clinician review or candidate screening — it is an over-the-counter supplement, not a prescribed protocol
Oral NAD+/NMN bioavailability is debated and, like nasal NAD+, lacks rigorous cognition outcome trials
No nurse or dietitian support; you are on your own for dosing and questions

Visit Renue By Science Shown for honest comparison — verified on the provider's own site in 2026.

Side by side

The honest comparison at a glance. “Flat pricing” means a single all-in monthly figure with no separate membership, starter, or per-format fee.

Provider	Price	Flat pricing	Clinician-reviewed	Pharmacy	Nurse/RD support
CoreAge RxFeatured	$93/mo flat	Flat pricing: yes	Clinician reviewed: yes	503A	Nurse/RD support: yes
AgelessRx	From $185/mo	Flat pricing: no	Clinician reviewed: yes	Network	Nurse/RD support: no
HydraMed	$299/mo	Flat pricing: no	Clinician reviewed: yes	Network	Nurse/RD support: yes
Hone Health	~$190/mo	Flat pricing: no	Clinician reviewed: yes	Network	Nurse/RD support: no
Invigor Medical	From $340/mo	Flat pricing: no	Clinician reviewed: yes	Network	Nurse/RD support: no
Tru Niagen	$49 (oral)	Flat pricing: no	Clinician reviewed: no	Retailer (none)	Nurse/RD support: no
Thorne (NiaCel 400)	Pricing varies	Flat pricing: no	Clinician reviewed: no	Retailer (none)	Nurse/RD support: no
Renue By Science	$84.95 (oral)	Flat pricing: no	Clinician reviewed: no	Retailer (none)	Nurse/RD support: no

Prices and program details verified on each provider's own site in 2026 and can change without notice. Tru Niagen, Thorne, and Renue By Science are supplement retailers, so “clinician-reviewed” is correctly marked no — they ship an over-the-counter product, not a prescribed protocol. Confirm current terms with the provider before starting.

Why CoreAge Rx ranks first

CoreAge wins on the fundamentals, not on any claim that NAD+ is a miracle. The price is genuinely flat — $93/month for the nasal spray or the injection, with no membership, starter fee, or lab surcharge to discover later. The intake is reviewed by U.S.-licensed clinicians, the NAD+ is filled by a 503A compounding pharmacy, and every plan includes 1:1 consults with a nurse and a registered dietitian. If you are not approved, you are refunded automatically.

We are also honest about the science: there is no rigorous trial showing nasal or injected NAD+ improves cognition or energy in people, and compounded NAD+ is not an FDA-approved product. This ranking is about provider quality, value, and experience — not a promise of sharper focus. Read the full picture in our NAD+ evidence review before deciding.

Start with CoreAge Rx — $93/mo

How we rank

We do not run sponsored reviews or accept payment to move a provider up the list. Rankings weigh four factors, with price transparency carrying the most weight because hidden recurring fees are the most common way NAD+ programs end up costing more than they first appear.

Price transparency

We reward a single, all-in monthly price. Plans that stack a membership, starter fee, or per-format surcharge on top of the medication rank lower than a true flat rate.

Clinician oversight

Real review by U.S.-licensed clinicians of an online intake, with a clear path to decline patients who are not appropriate candidates. Over-the-counter supplements have none.

Pharmacy quality

We note whether the compounding pharmacy is identified (e.g. a 503A facility) rather than left vague — and call out retailers that ship an unprescribed supplement.

Human support

Included access to a nurse or registered dietitian — not just a shipped vial — meaningfully improves the experience and is rare at this price point.

Read the evidence first

A provider ranking is only half the decision. Understand what NAD+ can and cannot do — and what actually drives brain fog — before you start:

This page is informational and not medical advice. Prescription NAD+ is available only after clinician review; compounded NAD+ is not FDA-approved, and oral NAD+/NMN supplements are not evaluated by the FDA to treat any condition. There is no rigorous trial showing nasal, injected, or oral NAD+ improves cognition or energy in people. Talk to a licensed provider about whether it is appropriate for you.